Molecule GEN is an automated, AI-driven one-stop platform for in-silico computational drug discovery. Molecule GEN enables researchers to accelerate drug discovery by equipping them with all the necessary information at their fingertips and automating many manual processes. Its built-in intelligence and heuristics allow users of all skill levels and backgrounds, viz., biologists, chemists, and AI researchers alike, to effectively translate their research ideas in no time and expedite the discovery of new therapeutic candidates. As a SaaS (software as a service) platform, Molecule GEN does away with the complex setup and maintenance processes and offers a frictionless way to use many built-in, tailor-made workflows for rational and AI-based de novo drug design. The platform offers well-curated and filtered building blocks with ease of use and also enables insights into uncharted territory and optimizes success rates. The platform is continuously enhanced by incorporating new modules offering state-of-the-art generative models for drug design.